An interesting point would be that if S. aureus becomes resistant to lugdunin (a matter of a few years maybe), S. lugdunensis might evolve naturally to find a new antibiotic.
So a similar study in a few years might lead to a new antibiotic molecule targetting the mutated S. aureus.
I was just thinking something similar - maybe the future for bacterium-specific treatments isn't to try and find a new antibiotic, but rather to pit different nasty bacteria against each other in an endless in-vitro cage match, then analyze the winner to learn their tricks?
So a similar study in a few years might lead to a new antibiotic molecule targetting the mutated S. aureus.
Is there hope for this or is it nonsense?