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We are running scans with 64 directions that are 8ish minutes, they look good. I'll have a look when I get into work, because there is obviously a large difference between their sequences and ours. Ours are not product sequences but they aren't anything too radical. Edit: to step further back, are you aware of anything that these undoubtably better scans offer in a clinical setting? How will they change treatment? We would run DTI occasionally when some surgery is planned and the surgeon wants to avoid a particular tract, but this isn't a common occurance.



Interesting, thanks. I didn't realize multiband was so fast on the Skyra - good to know.

The big advantage in principle for neurosurgery is better resolution of crossing fibers and complex branching, for example the lower/lateral projections of the CST to hand area. I'm not sure if any clinical software can take advantage of these scans, yet, though -- so processing would probably need to be done under IRB in researchy software. There's also ongoing work in several groups to better resolve and possibly even characterize tissue microstructure in and around tumors using multi-shell DWI (especially relating to edema).

Here's one small study that compared several high-angle methods to standard DTI: http://www.ncbi.nlm.nih.gov/pubmed/23254805

Walt Schneider's group at Pitt has also done studies in neurosurgery planning and TBI using HARDI-type methods (no cite handy at the moment).


Checked. Siemens 3T Skyra 2x2x2mm 104 directions, multibanded 6:32. Research scan.




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