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One diet that reflects these findings and is tested personally is "5:2 fast diet, proposed by M. Mosley. This method really is effective in reducing the ill effects of modern food and lifestyle and is easy to turn into normal weekly behavior pattern. https://thefastdiet.co.uk/


That sounds like a typical fad diet. What differentiates it, and what evidence do they have for their claims?


The companion documentary (Eat, Fast, and Live Longer) is worth watching - https://vimeo.com/50912488

Personal note: I've been following this diet since Jan 1. I also run ~ 70 miles/week. I've run 3 of my best marathons this year and lost 5 stubborn lbs (145 -> 140, I'm 5'8"). There are other styles of intermittent fasting. I'm enjoying this way of eating.

Aside, a related BBC/Horizon documentary I saw years ago flipped the question of obesity on its head and asked: Why Are Thin People Not Fat?

https://www.youtube.com/watch?v=U1hbPXooB1U


One of the problems with the word "diet" is the implicit connotations with fad-y short-term weight management strategies that never last. The same thing happens with the word "fast", but the implications are often religious. It's very easy to dismiss 5:2 for these reasons.

Looking at 5:2 simply as a "pattern of eating", however, makes it easier to consider not only the apparent health changes but also other potential benefits, including:

- Reduction of IGF-1 - Prolonged period of not eating as a means to promote cell repair - Shining a light on the cultural norms around eating three square meals a day with/without snacks in between.

After watching the documentary it seems like 5:2 may be more than just another "fad" diet.


I can link to this good artice in The Americal Journal of Medicine, Achieving Hunter-gatherer Fitness in the 21st Century: Back to the Future. http://www.amjmed.com/article/S0002-9343(10)00463-8/pdf

And the subsequent discussion on HN: https://news.ycombinator.com/item?id=10863626


Funny, I do the other way around! 5 days fast, 2 days eating. I think a 2 day fast is a bit harsh; you 'pay' the price of hunder the first day, but only have one day really of 'benefiting' from it...

In my case if I have to do it, I'd rather pay the price the first day, then keep the momentum. Also the third/fourth day there is a payout as you get a nice 'mental high'...

And blimey, the friday evening you can eat anything and it'll taste heavenly :-)


That's a great way to do it. There's so many benefits to intermittent fasting. Research shows it can: reduce oxidive stress on DNA, thus reducing Cancer. Plus it helps you eat fewer calories in a day. It reduces inflamation. It reduces the chance of type 2 diabetes. It even helps you produce BDNF which reduces the chance of mental disorders like parkinsons! Plus many more benefits, too many to list here...

Right now, alot of dieticiens are still behind the research, but they're slowly getting caught up.

Even the new york times published an article admitting that breakfast was not the most important meal of the day. they showed metastudies that showed there was absolutely NO evidence that showed breakfast was better for your health (other than some correlation based studies). It's time to jetison breakfast and live as our ancestors lived - the way we evolved to live. Nobody back then ate 3 meals a day - this is a new phenomenon started recently within the last several hundred years. the roman army conquered all of europe on just 1 meal a day: called lunch, and they got more excercise than any of us. And before that, people ate infrequently because the food supply was so unstable, often going for days without food.


With most 5:2 diets, you are not supposed to fast two consecutive days.

Non the less 2:5 sounds cool; please come back to report your experience! :)


Oh I've been doing it for years! As soon as I notice the waistline expanding, or I feel like a bit of 'detox', I try to schedule myself on a week where the fridge isn't too full of nice and/or perishable things, and I have a good mean on sunday night.

Then it's occasional fruit juice in the morning (bit of an energy boost) and coffee only until the friday.

It's a lot easier than it sounds, the 'key' thing is preparation; pick a week were you don't have a lot of 'social' to do, or any heavy physical things planned, and near empty fridge is good; instruction to the family not to decide to cook your favorite meal during the week and so forth.

Otherwise it's as reported; hunger on the first day mostly, then nothing; you get a bit of a metallic taste in the mouth, but tolerable... You get what I only can describe as a 'high' on the third/fourth day.

I lose roughly 1Kg a /day/ with that method, so if you do it once every quarter or so, that's largely enough to make up for some the odd chrismas/party/easter and so on :-)


This isn't for everyone. I had a period when I got really into fasting (I loved the challenge), often doing 24 hour and 48 hour fasts.

However, one time I tried to go for three days, and on the third day I got suddenly extremely lightheaded while hanging out with friends, and it was a scary enough that they insisted I end the fast right there (I agreed). My enthusiasm for fasting was tempered quite a bit after that.

Maybe that wouldn't happen the next time I tried going 3+ days, but I don't want to risk it.

Also, I've noticed that driving any serious distance while even on the second day of a two day fast, or concentrating on hard programming problems, can be pretty difficult. That's the main reason I don't do it much anymore (I was in high school and had nothing better to do when I was fasting before).


Fasting in the 5:2 method does not mean not eating all day. It means reducing the amount of calories to 1/4 of typical daily value. Usually it comes to having light breakfast, 180-220 kcal, skipping lunch and finishing the day with 250-350 kcal dinner.


I'm not informed on this topic - but isn't this dangerous? I mean, if your numbers are correct, an average adult loses 6% of their bodyweight doing this over 5 days. How does this affect your productivity and sleep?


It's practically impossible that that is all body fat. 1kg is over 7000 calories.

The body is more than 50% water, so weight is highly variable based on water retention, and fasting causes the body to excrete a lot of water.

For one, no salt intake will cause you to lose water. Secondly, glycogen depletion also causes you to lose water. The metallic taste in the mouth is ketosis, proof of glycogen depletion.


I used to do it on and off for a year or more 15 years ago.

I did it just for fun but noticed significantly improved productivity during the week.

I too would drink juice in the morning and possibly juice or 2 sugarcubes at lunch but not always and no calories otherwise.

To ease into fasting I would start by skipping dinner. Skipping breakfast was then easy (for me at least) and the rest of the week was no problem.

Then during a boring week in the military I decided to test what I had heard that we have 80% left when we feel completely exhausted. So after a couple of days of my "normal" fasting (IIRC) I skipped even my breakfast juice and continued without. Later that day I went to the gym and started lifting weights. 15 minutes into that I was completely drained and I was shaking for hours afterwards (again IIRC). That was my last time. :-/

I want to try again, but with a family it is way harder (and that experience kind of scared me.)


This honestly sounds like some kind of eating disorder.


Or hacker news :-)

In this case: body/mind hacking.




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