Great way to kill a city's economy. Instead of the bookstore I go to (which often requires me to come twice for a given book), I will now order online. I will not window-shop, and I will not find that cool-looking sweater in the store next to the bookstore. I will also not have a coffee at he cafe on the way to the garage.
My monies will no longer benefit these businesses, and if enough people stay away, they will eventually have to shut down. Storefronts will be boarded up, meanwhile, somewhere next to an interstate, another Amazon Warehouse grows.
This trend has already started, especially in small-to mid-sized European cities (large ones seem to hang on a bit longer, mostly because their public transit systems were heavily updated in the late 20th century). But even in Berlin, or Munich, or Paris I start noticing storefront rot - increasingly more shops, often specialized ones (which served as focal points for customers from afar who might then use that day to do secondary purchases) go out of business.
In the end, you will have very dense city centers filled with large-brand stores, next to major traffic hubs, and slums around it. Cities will lose their one major advantage: the desirability of living there.
