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Depends on the project but I think React(and other JS frontends) are heavily overused. Nothing wrong with good old HTML sites. Think twice for falling into the SPA trap. Not saying SPAs are a bad choice.


Currently integrating Keycloak as auth service for multiple existing projects. It's very advanced, many use cases and configurations are possible. We are in the middle of the migration but so far it hasn't been hard to integrate.

It's a rather large dependency so I won't recommend it for a single project with straight forward auth requirements.


I'm wondering, is there a hacker news for biohacking related stuff?

I have the feeling that there is a lot of progress being made in gene therapy technology these days. Having a friend who's life would be enhanced by gene therapy, I'm highly interested!


Gene therapy has had some recent successes [0], but it is worth noting that many of the ongoing and recent clinical gene therapy trials don’t necessarily involve genome editing: go to clinicaltrials.gov, search ‘gene therapy’ and get 3741 results. Search ‘CRISPR’ or ‘TALEN’ and get ~21 results.

Edit: I should say that most of the gene therapy clinical trials don’t involve genome editing yet. Though it seems to me that, at least for some diseases, viral vectors that deliver DNA to cells without integrating DNA into the host cell genome (where the dna instead persists inside the cells episomally, and is maybe lost from the cells after some number of divisions) will have advantages over integrating vectors/genome editing-based approaches. That way, you don’t have to worry about the off-target effects of genome editing, and you have a treatment that doesn’t result in permanent changes to the genome.

[0] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4879992/


Closest I know of is Fierce Biotech https://www.fiercebiotech.com/


thanks a lot!


Sadly, I don't think so. Check your local meetups. Additionally, SynBioBeta has been an ok source for recent biotech news.


Lobste.rs is open source and you could potentially spin up an instance of it specific to some topic you're interested in.

https://write.narwhal.space/ was an attempt at making an instance for writers, but it seems to have gone into disrepair.


I have exactly the same experience(two years of RN).

Be conservative when adding dependencies, rather try to solve it yourself unless it's very complex and the dependency is well maintained.

Often dependencies will cause you problems when upgrading and many maintainers don't respect semver(could be a JS-ecosystem issue).


There is, but it seems to be disabled by default.

https://docs.docker.com/engine/security/trust/content_trust/


This.

Most websites are mainly read only anyway. No need to throw in a programming language and store the data in a database.

The thing is, non-tech savvy people should be able to use(and deploy) and understand the static-web generators.


Have you thought how(or if) GDPR will affect your product?


Hi sphix0r, yes. First off we only store logs from user requests for 24hrs and only for analytics. Otherwise our GDPR compliance is still something we're perfecting but something we believe we're already on the right side of.


Actually used the same "hack" years ago. Made an app for a friend where one could import photos and drag logos on top of the photo.

Making a screenshot was way easier and since I didn't had to spend time to figure out how to use the bitmap API and its edge cases. Especially large pictures on low end devices caused crashes.


Yes, and it will also give more insight in what and how they collect and process your data.

GDPR would be a nice "tool" to validate the actual deletion of personal data.


Great to see protonmail working on this.

It's shocking how much sensitive data is sent by mail (contracts, passwords, lawyers, etc..) without pgp signing / encryption on a daily basis.


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