True, I used zoom about a month ago and it's still running a process in the background.

Um, why haven't you killed it?

Anyone care to explain the risks of using this drug?

- I know one must get tested for G6PD deficiency or it may lead to a hemolytic crisis. But I'm unsure how probable one is to have it or how long until this potential problem arises.

- I heard this drug can cause heart attacks in some people, Can this be predicted by a test? Some users on r/covid19 were advising against taking it without doctor supervision in a hospital for this reason but didn't explain nor gave statistics, as usual. The problem was related to prolonged qt intervals

For one, hydroxychloroquine, and especially when used in combination with azithromycin, can cause prolongation of an electrocardiogram interval called QT. The degree of QT prolongation is associated with a risk of sudden cardiac death. QT prolongation is an issue in patients with underlying heart disease or electrolyte abnormalities. QT > 500 is associated w/ increased risk of sudden death.

> The other major disadvantage is that these drugs can interact with protease inhibitors

What are the possible consequences of this?

Death.

Kaletra, a protease inhibitor, is a combination of two drugs, one of which is a CYP3A4 inhibitor. It is used with some success on coronavirus patients.

Co-administering this with chloroquine 500mg/BID could easily result in chloroquine concentrations well above LD50.

Don't mix it with hydroxychloroqine. They can cause a heart attack when combined.

prolonged qt interval. Yeah.

Can anyone mention a reasonable explanation for the 6-month delay? All I can think is that they want to prevent irresponsible purchases thus only including it in treatment guidelines for now.

I think the 6 month delay relates to patient by patient data. They can release group statistics before.

maybe they forgot to change that page on their powerpoint template? I know I've done it.

just HN, this is not javascript