In Bioinformatics/DNA sequencing I'm probably most excited by Illumina's push toward a 100USD genome.

Their current scale-up of instruments I think means that they're looking to aggressively push into diagnostic applications.

The lack of competition is unfortunate however.

Long reads from PacBio, Oxford Nanopore, and 10x are also exciting. This new tech coupled with HiC for scaffolding and single cell sequecing brings up the possibility of complete knowledge of your genome, the collection of strains in a metagenome, or all the types of cells in a tissue/cancer sample.

Sub 1K full-genome sequencing is what I'm in love with. I'm eagerly awaiting any breakthroughs there.