Hacker News new | past | comments | ask | show | jobs | submit | TomHenderson3's comments login

I would like to understand why they seemed to use internet domains as proxies for nations.


It's not just soft power. It is also economic power. Also, note that there is a baseline 10% on all countries.


You are misinterpreting the study. They are interested in the change in lean body mass wash-in to post RT because that is the lean body mass that can be attributed to more than just the initial increase from simply taking creatine. The increase in females that you cite is including that initial increase, which is not interesting.


So you know, they are misunderstanding the paper.


"There were no group differences in lean body mass growth following resistance training in females (p = 0.10) or males (p = 0.35)"


It actually does if the other studies failed to control for the gains just during the loading period, which is what the study is claiming may be happening.


According to this paper, yes, the 1kg could very well just be water retention, or the increase in lean body mass during the loading period.


You may want to delete your comment as it is spreading misinformation about this study.


They can't delete the comment because 1) it is past the 2-hour deletion window and 2) it has replies.


Wait, are you saying that they didn't have the creatine arm of the study work as hard as the control arm? I'm really confused by this comment.


In the introduction they talk about creatine loading. Also, their study is looking at lean body mass changes after the "wash-in" period, so any effect that increased recovery is supposed to have on lean body mass when following the exercise protocol they give for the time period they studied should be captured, no?


> In the introduction they talk about creatine loading

(1) Yes, that the loading phase was BYPASSED. = (

"Those on creatine did bypass a loading phase, which includes taking 20 to 25 grams daily for up to one week. While it is common to start with a loading phase, it can cause gastrointestinal issues and is not necessary to reach saturation levels – the maximum that the body can store at any one time. "

My understanding, to reach saturation without a loading phase - it takes about 3 to 4 weeks. (Could be wrong, going off of memory there.)

With loading, I've read it takes 1 to 2 weeks to reach saturation.

(2) Without measuring creatine levels, what was even tested? How many people were creatine "non-responders?" How many people were getting plenty of creatine from their diets already?

(3) Was the creatine regimen effective and optimal? Water intake is another factor. I don't think a set of 50 people divided between 2 groups is going to be anywhere near enough to capture a nuance like efficacy of the regimen vs no regimen.

> Also, their study is looking at lean body mass changes after the "wash-in" period, so any effect that increased recovery is supposed to have on lean body mass when following the exercise protocol they give for the time period they studied should be captured, no?

I'd say no, simply because it is not known whether the wash-in period was actually a wash-in period without knowing if creatine levels actually changed in a significant way. Second, the study group of beginner weight lift lifters is a chaotic data set. The gains of lifting weights vs not lifting weights is likely magnitudes different from creatine vs no-creatine supplementation. Some beginners might easily get 10% more muscle mass vs 5% for others. An effect that is expected be very low is going to be completely lost in the noisy data. Let alone that we are starting from a questionable baseline.

Overall, since the body can absorb up to about 5g of creatine a day, and the body is likely already intaking 1 or 2g per day - this study is kinda only looking at the effect of an increase of creatine from a moderate dosage to a maximal dosage, across beginner weight lifters. It's like, say you're a bit dehydrated, instead of drinking 500ml of water per day, you now start drinking 550ml of water and then measure any changes from starting a brand new weight lifting routine.


Consider applying for YC's Summer 2025 batch! Applications are open till May 13

Guidelines | FAQ | Lists | API | Security | Legal | Apply to YC | Contact

Search: