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That was not my experience at all when I used to drink, and I don't think I'm alone in this. The feeling from different alcoholic drinks differed significantly.

I definitely see effects on my glucose the day after when I change my exercise routine, such as doing an extra LISS session. Anticipation of something stressful or exciting does also have an effect. I haven't noticed any effect from simply expecting more exercise later (without emotions attached). I believe a lot of this comes down to liver and muscle glycogen storage and release. (I'm T1)


And one reason for taking B12 is actually to prevent neuropathy.


Looking at the interactions in metabolism, I don’t see it.

A low B6 diet and focus on conversion to P5P and oxidation of the excess (Aldehyde Oxidase, and maybe by proxy the ALDHs) is a safer bet.



I remember reading about a physical device someone constructed with mirrors (I think at an early burning man) that gave you the experience of a huge inter ocular distance to get a giant's eye view. I've always wanted to try one (or the opposite to experience a tiny inter ocular distance).



A pair of periscopes laid flat will do it, but it'll really confuse your eyes. I can feel it on these images: the eye muscles are trying to converge on a distance closer than the focusing muscles want to focus on, and I can tell that's a bit weird. That might be an age thing though.


You get the same thing with VR headsets as their physical focus is always around 1 metre away (3-4 feet). But you get used to it quickly.


I have noticed too that HN has an enduring fascination with quaternions, and they seem to reach front page surprisingly frequently (considering that there's not a huge amount of discussion of other geometry topics). I'm certainly not complaining though - I love quaternions too!


A few years back I made this 3d visualisation https://x.com/KangarooPhysics/status/1253336959755251716


Wow, this made everything click for me. Really nice animation!


Also when figuring out how much insulin is needed for a given amount of carbs you need to factor in the type of carbs, your individual response to that type of carbs, what fats/protein/fiber you eat with it (fats and fiber tend to slow down the BG rise from carbs, protein can cause a rise when eaten on its own but can also slow down the rise from carbs), what time of day it is (I need around double the amount of insulin for the same food first thing in the morning vs in the afternoon), your mood, what else is in your stomach already, the weather (hot weather can greatly increase insulin sensitivity), your current fitness level, what physical activity you have done over the last day or 2 and what you will do over the coming hours, where on your body you inject, if you are fighting any illness…


For my wife (type 1 diabetic), physical activity is the big one that throws off her calculations as a walk in a hilly area makes her blood sugar drop like a rock. Of course she always has something with sugar with her but then she has to figure out how much to consume.


Hill walks are particularly challenging for me too. I can do rowing or weightlifting with my sugars staying fairly stable or rising if it's really intense, but something about walking steadily up a gentle slope makes it drop massively. There was some interesting research a couple of years back on how exercising the calf muscle is particularly effective at lowering BG, perhaps that has something to do with it https://pmc.ncbi.nlm.nih.gov/articles/PMC9404652/


Yea, as a T1D myself the amount of insulin I need is massively different from days I'm arguing on the internet compared to days I'm up doing physical exercise. Things get concerning really quick when you're a distance from anything and your glucose starts dropping.


I was expecting a head mounted display that somehow unlocks things


You might be interested in this recent work in the 3mf format

https://cdfam.com/3mf-consortium-volumetric-and-implicit-ext...


I made an animation comparing the reef and thief knots that maybe makes it a little more intuitive why one is stronger: https://x.com/KangarooPhysics/status/1526265820220952582


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