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Physician here. I read this paper when it was posted on Reddit a few days ago and it was very impressive.

I'll link to the discussion because the top comment was comprehensive and summarizes the published article:

http://www.reddit.com/r/science/comments/22qhob/laboratorygr...

To address questions of how this can be applied to other organs, growing tissue like a trachea or skin is becoming easier. They grow the cells on a scaffold and then you have a tissue. Organs are much more complex and a penis is an organ. We are not at that level of sophistication to grow an entire, functional organ ex-vivo, at least for human use.



Do you have any insight into what would be the effect of this on Sex Reassignment Surgeries?


I wish I did. It's by no means an area of expertise for me, but I would guess that this technique is extremely expensive and will remain limited--at least for the short term--to use in cases of genetic females that require replacement of their vagina due to its congenital absence of loss from cancer/injury.

The location of blood vessels, nerves, etc. is different in genetic male vs. female and may require a totally different approach.


Unfortunately, limited for now. The implantation was done in patients who have most of the "infrastructure" already in place, rather than the somewhat more dramatic restructuring required for sex reassignment surgery.

But it is a very promising first step.




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