Type-safety is hard with macros; you can't use a macro as a function pointer, for the obvious reason that it's not a function; such macros would tend to trample all over libc functionality, and glibc is not the only libc; the kernel and userland should arguably be separate.
It wouldn't be too hard to create (generate) a "libwrapsyscall" that just provided syscalls; if this is worth doing, it's worth doing properly.
How about 'static inline' functions distributed along with the libc header files? You get type / number of arguments correctness and no ABI bloat, at the cost of having (minimal) code in header files and per-object code duplication (possibly solved by an intelligent cc/ld).
It wouldn't be too hard to create (generate) a "libwrapsyscall" that just provided syscalls; if this is worth doing, it's worth doing properly.