Enzymatic cofactors (vitamins) many not a be cure, but maybe a better, cheaper, less harmful, treatment. Take pyridoxine (B6) as an example.
Also, did you know vitamin C deficiency not only casues scurvy but mood disorders as well?
The neuropsychiatric effects of vitamin C deficiency: a systematic review
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7302360/
Vitamin B6 as add-on treatment in chronic schizophrenic and schizoaffective patients: a double-blind, placebo-controlled study
https://pubmed.ncbi.nlm.nih.gov/11838627/