I use several different browsers. I have one completely locked-down (no images, js, cookies, etc), exceptions by whitelist-only + host blocking. That one is used for most of my daily browsing. I use a separate browser for anything that requires webapps or cookies, and an entirely different computer for anything financial or important. The only problem I have is occasionally being frustrated by how bad the Chrome and Firefox UIs are compared to literally anything else, or even themselves a few years ago.