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It's hard to separate the impacts of plain nicotine from the impact of cigarettes because the literature is almost entirely focused on smokers, and scientific writing sometimes conflates the two. That said,

> Nicotine constricts blood vessels, including those in the skin and coronary blood vessels, but dilates blood vessels in skeletal muscle. Vasoconstriction of the skin results in reduced skin blood flow and reduced fingertip skin temperature.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4958544/




Vessel constriction or dilation by itself is not necessarily a bad thing. CO2 is a potent vasodilator, but no one would claim holding/pacing your breath for swimming is a bad thing. Caffeine too has a strong vasoconstricting effect.


Sure, I was not trying to make the claim that constriction or dilation was a bad thing.




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